Depersonalization disorder is produced by a conglomerate of intense egos, especially within the emotional center. Anxiety can often trigger it, which are also a constellation of different egos of fear, anxiety, tension, etc.
Self-observation does not mean you lose touch with reality. It means to see yourself as you are. The ultimate technique for this is daily meditation.
How often are you meditating to comprehend and eliminate your defects?
Do you vocalize mantras for your heart, like Om Masi Padme Hum, for an hour daily?
Do you practice chastity? If so, what and how?
You heal your heart, overcome anxiety, and stabilize your human machine through chastity, sanctity, and service.
You should also seek professional help if your symptoms are interfering with your personal, social, professional life, etc.